A field study on the evaluation of safety and effectiveness of the attenuated Infectious Bursal disease vaccine when applied to day-old chicks at the hatchery
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Abstract
The study was conducted to evaluate the safety and effectiveness of a new attenuated Gumboro vaccine, MB-1 in Luong Phuong chickens. A total of 27,700 one-day-old Luong Phuong chicks were vaccinated with the MB-1 vaccine at a dose of 0.1 mL/bird at the hatchery. The results showed that the level of IBD maternal antibodies on the day of vaccination reaching an average titer of 4,857. The MB-1 vaccine virus was in the Bursa of Fabricius from 24 to 36 days old. The Bursa Lesion Score (BLS) was moderate; gradually increased from 0.67 to 3 points and decreased with signs of recovery to 2.33 points at 36 days of age. The Bursa Index at 21 days of age was 0.39% and decreased to 0.1% at 36 days of age. The humoral immune response to ND vaccination was high, reaching an average titer of 4,448 at 42 days of age. Especially, MB-1 induced a strong immune reaction leading to high IBD antibody titers and more uniformity, reaching an average titer of 3,632 with a low CV of 22%. In summary, the application of MB-1 vaccine at the hatchery would provide one-day-old chicks with early localization of the vaccine virus in the Bursa and rapid and uniform development of active IBD antibodies. The MB-1 vaccine did not affect the immune response of chicks to the ND vaccination and was safe for the Bursa when applied to commercial day-old broiler chicks at the hatchery.
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Ashash, U., Noach, C., Perelman, B., Costello, C., Sansalone, P., Brazil, T., & Raviv, Z. (2019). In ovo and day of hatch application of a live infectious bursal disease virus vaccine to commercial broilers. Avian Diseases 63(4), 713-720. https://doi.org/10.1637/aviandiseases-D-19-00087
Boudaoud, A., Mamache, B., Tombari, W., & Ghram, A. (2016). Virus mutations and their impact on vaccination against infectious bursal disease (Gumboro disease). Revue scientifique et technique (International Office of Epizootics) 35(3), 875-897. https://doi.org/10.20506/rst.35.3.2576
De Wit, J. J., Heijmans, J. F., Mekkes, D. R., & Van Loon, A. A. (2001). Validation of five commercially available ELISAs for the detection of antibodies against infectious bursal disease virus (serotype 1). Avian pathology: journal of the W.V.P.A. 30(5), 543-549. https://doi.org/10.1080/03079450120078743
Eterradossi, N., & Saif, Y. M. (2013). Infectious Bursal Disease. In Swayne, D. E. (Ed). Diseases of Poultry (13th ed, 219-246). Hoboken, New Jersey: John Wiley & Sons, Ltd. https://doi.org/10.1002/9781119421481.ch7
Farhanah, M. I., Yasmin, A. R., Khanh, N. P., Yeap, S. K., Hair-Bejo, M., & Omar, A. R. (2018). Bursal immunopathology responses of specific-pathogen-free chickens and red jungle fowl infected with very virulent infectious bursal disease virus. Archives of virology 163(8), 2085-2097. https://doi.org/10.1007/s00705-018-3841-7
Gomes, L., Ashash, U., Banet-Noach, C., Finger, A., & Neto, R. J. P. (2015). A field study on broiler flocks in Brazil to evalua zootechnical parameters, molecular epidemiology, and condemnation index with the use of Live IBD Vaccine versus HVT-IBD Vector Vaccine. Retrieved September 29, 2018, from http://www.wvpa.net/pdfs/articles/WVPC-2015-AB_058.pdf
Haddad, E. E., Whitfill, C. E., Avakian, A. P., Ricks, C. A., Andrews, P. D., Thoma, J. A., & Wakenell, P. S. (1997). Efficacy of a novel infectious bursal disease virus immune complex vaccine in broiler chickens. Avian Diseases 41(4), 882-889.
Iván, J., Velhner, M., Ursu, K., Germán, P., Mató, T., Drén, C. N., & Mészáros, J. (2005). Delayed vaccine virus replication in chickens vaccinated subcutaneously with an immune complex infectious bursal disease vaccine: quantification of vaccine virus by real-time polymerase chain reaction. Canadian Journal of Veterinary Research 69(2), 135-142.
Jeurissen, S. H., Janse, E. M., Lehrbach, P. R., Haddad, E. E., Avakian, A., & Whitfill, C. E. (1998). The working mechanism of an immune complex vaccine that protects chickens against infectious bursal disease. Immunology 95(3), 494-500. https://doi.org/10.1046/j.1365-2567.1998.00617.x
Kurukulasuriya, S., Ahmed, K. A., Ojkic, D., Gunawardana, T., Goonewardene, K., Gupta, A., Chow-Lockerbie, B., Popowich, S., Willson, P., Tikoo, S. K., & Gomis, S. (2017). Modified live infectious bursal disease virus (IBDV) vaccine delays infection of neonatal broiler chickens with variant IBDV compared to turkey herpesvirus (HVT)-IBDV vectored vaccine. Vaccine 35(6), 882-888. https://doi.org/10.1016/j.vaccine.2017.01.005
Lazarus, D., Pasmanik-Chor, M., Gutter, B., Gallili, G., Barbakov, M., Krispel, S., & Pitcovski, J. (2008). Attenuation of very virulent infectious bursal disease virus and comparison of full sequences of virulent and attenuated strains. Avian Pathology: Journal of the W.V.P.A 37(2), 151-159. ttps://doi.org/10.1080/03079450801910206
Le Gros, F. X., Dancer, A., Giacomini, C., Pizzoni, L., Bublot, M., Graziani, M., & Prandini, F., (2009). Field efficacy trial of a novel HVT-IBD vector vaccine for 1-day-old broilers. Vaccine 27(4), 592-596. https://doi.org/10.1016/j.vaccine.2008.10.094
Mazariegos, L. A., Lukert, P. D., & Brown, J. (1990). Pathogenicity and immunosuppressive properties of infectious bursal disease" intermediate" strains. Avian diseases 34(1), 203-208.
Moraes, H. L. S., Salle, C. T. P., Padilha, A. P., Nascimento, V. P., Souza, G. F., Pereira, R. A., Artencio, J. O., & Salle, F. O. (2004). Infectious bursal disease: Evaluation of pathogenicity of commercial vaccines from Brazil in specific pathogen free chichens. Brazilian Journal of Poultry Science 6(4), 243-247. https://doi.org/10.1590/S1516-635X2004000400009
MOST (Ministry of Science and Technology of Vietnam). 2011. TCVN9117:2011: Breeding poultry – Technical requirements. Ha Noi, Vietnam: Ministry of Science and Technology.
Müller, H., Mundt, E., Eterradossi, N., & Islam, M. R. (2012). Current status of vaccines against infectious bursal disease. Avian Pathology: Journal of the W.V.P.A. 41(2), 133-139. https://doi.org/10.1080/03079457.2012.661403
Muskett, J. C., Hopkins, I. G., Edwards, K. R., & Thornton, D. H. (1979). Comparison of two infectious bursal disease vaccine strains: Efficacy and potential hazards in susceptible and maternally immune birds. The Veterinary record 104(15), 332-334. https://doi.org/10.1136/vr.104.15.332
Olesen, L., Dijkman, R., Koopman, R., van Leeuwen, R., Gardin, Y., Dwars, R. M., de Bruijn, N. D., Boelm, G. J., Elattrache, J., & de Wit, J. J. (2018). Field and laboratory findings following the large-scale use of intermediate type infectious bursal disease vaccines in Denmark. Avian pathology : Journal of The W.V.P.A. 47(6), 595-606. https://doi.org/10.1080/03079457.2018.1520388
Perozo, F., Villegas, P., Fernandez, R., Cruz, J., & Pritchard, N. (2009). Efficacy of Single Dose Recombinant Herpesvirus of Turkey Infectious Bursal Disease Virus (IBDV) Vaccination Against a Variant IBDV Strain. Avian Diseases, 53(4), 624–628. https://doi.org/10.1637/8687-31009RESNOTE.1
Quach, A. T., Le, H. T., Nguyen, H. M., & Le, A. T. T. (2018). Field assessment of the efficacy of M.B., LIBDV and Winterfield 2512 strain vaccines against infectious bursal disease in chickens. The Journal of Agriculture and Development 17(6), 15-23. https://doi.org/10.52997/jad.3.06.2018
Rautenschlein, S., Kraemer, Ch., Vanmarcke, J., & Montiel, E. (2005). Protective efficacy of intermediate and intermediate plus infectious bursal disease virus (IBDV) vaccines against very virulent IBDV in commercial broilers. Avian Diseases 49(2), 231-237. https://doi.org/10.1637/7310-112204R
Ray, S. M., Ashash, U., & Muthukumar, S. (2021). A field study on the evaluation of day-of-hatch and in grow-out application of live infectious bursal disease virus vaccine in broiler chickens. Poultry Science 100(8), 101252. https://doi.org/10.1016/j.psj.2021.101252
Sellaoui, S., Alloui, N., Mehenaoui, S., & Djaaba, S. (2012). Evaluation of size and lesion scores of bursa cloacae in broiler flocks in algeria. Journal of World's Poultry Research 2(3), 37-39.
Sharma, J. M., Kim, I. J., Rautenschlein, S., & Yeh, H. Y. (2000). Infectious bursal disease virus of chickens: Pathogenesis and immunosuppression. Developmental and Comparative Immunology 24(2-3), 223-235. https://doi.org/10.1016/s0145-305x(99)00074-9
Skeeles, J. K., Lukert, P. D., Fletcher, O. J., & Leonard, J. D. (1979). Immunization studies with a cell-culture-adapted infectious bursal disease virus. Avian Diseases 23(2), 456-465. https://doi.org/10.2307/1589576
Van den Berg, T. P., Eterradossi, N., Toquin, D., & Meulemans, G. (2000). Infectious bursal disease (Gumboro disease). Revue scientifique et technique (International Office of Epizootics) 19(2), 509-543.