Use of Marine Sulfated Polysaccharide as an alternative to antibiotics in the diet of broilers
Main Article Content
Abstract
The objective of the experiment was to evaluate the efficacy of Marine Sulfated Polysaccharide enhanced by a blend of
organic acids (AseaD) as an alternative to colistin in the diet of broilers. A total of two hundred and sixteen one-day-old male chicks (Ross 308, initial body weight: 42.25 ± 0.42 g/bird) were randomly assigned to 1 of 2 treatments each represented with 12 replicate cages of 9 birds. The dietary treatments included (1) basal diet with antibiotic (Control, basal diet + 20 ppm colistin) and (2) basal diet without antibiotic + 0.3% AseaD (AseaD). Birds in the control were fed a basal diet containing colistin from 1 to 28 days of age only. There were no differences in ADG and ADFI between the 2 treatments at any phases or for the overall period (P > 0.05). Similarly, no differences in FCR were found during d 1-28 or the overall period (P > 0.05). Nevertheless, the FCR of broilers fed AseaD (1.893) was lower than that of broilers fed the control diet (1.991) from 29 to 42 days of age (P = 0.016). No differences in the survival rate of birds were found between the 2 treatments (P > 0.05). These results confirm the potency of AseaD in broiler diets as a potential alternative to colistin used at a concentration of 20 ppm, with significant benefits and interest during the finishing period when colistin is withdrawn from a diet.
Article Details
References
Adams, C. A. (2004). Nutricines in poultry production: focus on bioactive feed ingredients. Nutrition Abstracts and Reviews B 76(4), 1-12.
Ao, T., Cantor, A. H., Pescatore, M. J., Ford, M. J., Pierce, J. L., & Dawson, K. A. (2009). Effect of enzyme supplementation and acidification of diets on nutrient digestibility and growth performance of broiler chicks. Poultry Science 88(1), 111-117. https://doi.org/10.3382/ps.2008-00191
Berri, M., Slugocki, C., Olivier, M., Helloin, E., Jacques, I., Salmon, H., Demais, H., Goff, M. L., & Collen, P. N. (2016). Marine-sulfated polysaccharides extract of Ulva armoricana green algae exhibits an antimicrobial activity and stimulates cytokine expression by intestinal epithelial cells. Journal of Applied Phycology 28(5), 2999-3008. https://doi.org/10.1007/s10811-016-0822-7
Castanon, J. I. R. (2007). History of the use of antibiotic growth promoters in European poultry feeds. Poultry Science 86(11), 2466-2471. https://doi.org/10.3382/ps.2007-00249
de Jesus Raposo, M. F., de Morais, A. M., & de Morais, R. M. (2015). Marine polysaccharides from algae with potential biomedical applications. Marine Drugs 13(5), 2967–3028. https://doi.org/10.3390/md13052967
Fascina, V. B., Sartori, J. R., Gonzales, E., de Carvalho, F. B., de Souza, I. M. G. P., Polycarpo, G. V., Stradiotti, A. C., & Pel´ıcia, V. C. (2012). Phytogenic additives and organic acids in broiler chicken diets. Revista Brasileira de Zootecnia 41(10), 2189–2197. https://doi.org/10.1590/S1516-35982012001000008
Garcia,V., Catala´-Gregori, P., Herna´Ndez, F., Megi´as, M. D., & Madrid, J. (2007). Effect of formic acid and plant extracts on growth, nutrient digestibility, intestine mucosa morphology, and meat yield of broilers. The Journal of Applied Poultry Research 16(4), 555-562. https://doi.org/10.3382/japr.2006-00116
Ghazala, A. A., Atta, A. M., Elkloub, K., Mustafa, M. E. L., & Shata, R. F. H. (2011). Effect of dietary supplementation of organic acids on performance, nutrients digestibility and health of broiler chicks. International Journal of Poultry Science 10(3), 176-184. https://doi.org/10.3923/ijps.2011.176.184
Hassan, H. M. A., Mohamed, M. A., Youssef, A. W., & Hassan, E. R. (2010). Effect of using organic acids to substitute antibiotic growth promoters on performance and intestinal microflora of broilers. AsianAustralasian Journal of Animal Sciences 23(10), 1348-1353. https://doi.org/10.5713/ajas.2010.10085
Jun, J. Y., Jung, M. J., Jeong, I. H., Yamazaki, K., Kawai, Y., & Kim B. M. (2018). Antimicrobial and antibiofilm activities of sulfated polysaccharides from marine algae against dental plaque bacteria. Marine Drugs 16(9), 301-313. https://doi.org/10.3390/md16090301
Khan, S. H., & Iqbal, J. (2016). Recent advances in the role of organic acids in poultry nutrition. Journal of Applied Animal Research 44(1), 359-369. https://doi.org/10.1080/09712119.2015.1079527
Leonard, S. G., Sweeney, T., Bahar, B., Lynch, B. P., & O’Doherty, J. V. (2011). Effects of dietary seaweed extract supplementation in sows and post-weaned pigs on performance, intestinal morphology, intestinal microflora and immune status. The British Journal of Nutrition 106(5), 688-699. https://doi.org/10.1017/S0007114511000997
NRC (National Research Council). (1994). Nutrient Requirements of Poultry (9th ed.). Washington DC, USA: National Academy Press.
Panda, A. K., Rao, S. V. R., Raju, M. V. L. N., & Sunder, G. S. (2009). Effect of butyric acid on performance, gastrointestinal tract health and carcass characteristics in broiler chickens. Asian-Australasian Journal of Animal Sciences 22(7), 1026-1031. https://doi.org/10.5713/ajas.2009.80298
Rezaei, M., Yngvesson, J., Gunarsson, S., Jonsson, L., & Wallenbeck, A. (2018). Feed efficiency, growth performance, and carcass characteristics of a fast-and a slower-growing broiler hybrid fed low- or high-protein organic diets. Organic Agriculture 8(2), 121-128. https://doi.org/10.1007/s13165-017-0178-6
Singer, A. C., Shaw, H., Rhodes, V., & Hart, A. (2016). Review of antimicrobial resistance in the environment and its relevance to environmental regulators. Frontiers in Microbiology 7, 1728. https://doi.org/10.3389/fmicb.2016.01728
Tziveleka, L. A., Pippa, N., Georgantea, P., Ioannou, E., Demetzos, C., & Roussis, V. (2018). Marine sulfated polysaccharides as versatile polyelectrolytes for the development of drug delivery nanoplatforms: Complexation of ulvan with lysozyme. International Journal of Biological Macromolecules 118(Pt A), 69-75. https://doi.org/10.1016/j.ijbiomac.2018.06.050
Wang, J. P., Yoo, J. S., Lee, J. H., Zhou, T. X., Jang, H. D., Kim, H. J., & Kim, I. H. (2009). Effects of phenyllactic acid on production performance, egg quality parameters, and blood characteristics in laying hens. The Journal of Applied Poultry Research 18(2), 203-209. https://doi.org/10.3382/japr.2008-00071
Wang, T., Olafsd´ottir, G., J´onsdo´ttir, R., Kristinsson,´ H. G., & Johannsson, R. (2011). Functional and nutraceutical ingredients from marine macroalgae. In C. Alasalvar, K. Miyashita, F. Shahidi, & U. Wanasundara (Eds.), Handbook of seafood quality, safety and health applications. New York, USA: Blackwell.