Antibiotic sensitivity of common respiratory bacteria of pig from Hubei province, China
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Abstract
The use of antimicrobials for feeding and treatment is crucial to animal health. However, continuous use of antibiotics is contributing to emergence and widespread of antibiotic resistance. This study aimed to investigate the antimicrobial resistance of five major respiratory pathogens in pigs of Hubei province, China, from October to December, 2019. Antibiotic susceptibility testing for Streptococcus suis, Haemophilus parasuis, Pasteurella multocida, Bordetella bronchiseptica and Actinobacillus pleuropneumoniae was determined to representatives of relevant antibiotic classes.
Streptococcus suis isolates were mostly sensitive to beta-lactams, whereas high levels of resistance were observed to quinolones, gentamycin, doxycycline, trimethoprime and lincomycin. For H. parasuis, P. multocida and A. pleuropneumoniae of Pasteurellaceae family, the susceptibility to beta-lactams and quinolones was displayed. Most \textit{B. bronchiseptica} isolates were sensitive to doxycycline, azithomycin, polymycin whereas high resistance levels to beta-lactams, aminoglycosides and quinolones were recorded.
This study obtained practical data for later studies and usage to combat infections due to respiratory bacteria.
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References
Brownfield, B. (2013). Actinobacil lus pleuropneumoniae in swine. Purdue University-Animal Disease Diagnostic Laboratory. Indiana, USA.
Cheung, P. Y., Lo, K. L., Cheung, T. T., Yeung, W. H., Leung, P. H., & Kam, K. M. (2008). Streptococcus suis in retail markets: How prevalent is it in raw pork? International Journal of Food Microbiology 127(3), 316-320. https://doi.org/10.1016/j.ijfoodmicro.2008.08.006
CLSI (Clinical and Laboratory Standards Institute). (2018). Performance standards for antimicrobial susceptibility testing (28th ed.). CLSI document M100- S28. Pennsylvania, USA: Clinical and Laboratory Standards Institute.
Goyette-Desjardins, G., Auger, J. P., Xu, J., Segura, M., & Gottschalk, M. (2014). Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing. Emerging Microbes and Infection Journal 3(1), 1-20. https://doi.org/10.1038/emi.2014.45
Jeffrey, J. Z., Locke, A. K., Alejandro, R., & Kent, J. S. (2012). Diseases of Swine . Iowa, USA: Wiley- Blackwell.
Jong, A. D., Simjee, S., Garch, F. E., Moyaert, H., Rose, M., Youala, M., & Dry, M. (2018). Antimicrobial susceptibility of enterococci recovered from healthy cattle, pigs and chickens in nine EU countries (EASSA Study) to critically important antibiotics. Veterinary Microbiology 216, 168-175. https://doi.org/10.1016/j.vetmic.2018.02.010
Laxminarayan, R. (2013). Antibiotic resistance-the need for global solutions. Lancet Infectious Diseases 13(12), 1057-1098. https://doi.org/10.1016/S1473-3099(13)70318-9
Nagai, S., Someno, S., & Yagihashi, T. (1994). Differentiation of toxigenic from nontoxigenic isolates of Pasteurel la multocida by PCR. Journal of Clinical Microbiology 32(4), 1004-1010. https://doi.org/10.1128/jcm.32.4.1004-1010.1994
Nedbalcova, K., Satran, P., Jaglic, Z., Ondriasova, R., & Kucerova, Z. J. V. M. (2006). Haemophilus parasuis and Gl ̈asser’s disease in pigs: a review. Veterinarni Medicina 51(5), 168-179.
Xue, Y., Zhao, Z. Q., Chen, Y., Zou, H. Y., & He, Q. G, Li, W. J., Xiong, J. F., Chen, H. C. (2009). Development of a rapid multiplex PCR for stimultaneous detection of five major pathogenic bacteria of respiratory tract disease in swine. Journal of Animal Husbandry and Veterinary Medicine 40(8), 1222-1228.
Zhao, Z., Xue, Y., Wang, C., Ding, K., Wu, B., He, Q., Cheng, X., & Chen, H. (2011). Antimicrobial susceptibility of Bordetel la bronchiseptica isolates from pigs with respiratory diseases on farms in China. Journal of Veterinary Medical Science 73(1), 103-106. https://doi.org/10.1292/jvms.10-0184
Zhang, Q. Q., Ying, G. G., Pan, C. G., Liu, Y. S., & Zhao, J. L. (2015). Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance. Environmental Science Technology 49(11), 6772-6782. https://doi.org/10.1021/acs.est.5b00729