Efficacy of propylene glycol on prevention and treatment of ketosis for dairy cows in lactation stage
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Abstract
The objective of this study was to evaluate the efficacy of propy-lene glycol (PG) on prevention and treatment of ketosis in dairy cows from 09/2018 to 03/2019. The study consisted of 2 exper-iments using a total of 126 multiparous dairy cows in a HF crossbred herd. Cows in both experiments were randomly as-signed to treatments in a randomized complete block design. In Exp. 1, 96 cows without ketosis disease (BHB < 1.4 mmol/L) were assigned to 2 groups (48 cows/group), including (1) un-treated control group (no PG) and (2) treatment group (oral PG for 3 consecutive days after parturition). In Exp. 2, 30 ke-totic cows (BHBA < 1.4 mmol/L) were divided into 3 groups (10 cows/group), including (1) cows provided with glucose + vitamin B12 + dexamethasone (TT1), (2) cows treated with PG for 3 days (TT2), and (3) combination of TT1 and TT2 (TT3). The results of the Exp. 1 showed that the proportion of ketotic cows was lower (P < 0.01) in the PG-treated group (18.75%) than in the control group (47.92%). The PG treatment also reduced (P < 0.01) the blood ketone concentration of cows as compared with the control without PG use (0.89 vs. 1.22 mmol/L). In the Exp. 2, after treatment the reduction of blood ketone concentration was much greater (P < 0.01) in TT3 cows (1.97 mmol/L) than in TT2 cows (1.30 mmol/L) and TT1 cows (1.23 mmol/L). The percentage of cows recovered from ketosis was greatest in TT3 (90%), followed by TT2 (60%), and then TT1 (50%) (P > 0.05).
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