Effects of antibacterial peptides in non-antibiotic feeds on the productivity of growing pigs
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Abstract
The objective of this study was to evaluate growth performance of finishing pigs fed diets with two antibiotics or fed with organic originated supplements. A total of 48 crossbred weaned piglets were randomly assigned into four treatments and the study was conducted in 108 days. Each treatment had 06 replicates and 2 piglets (1 male and 1 female) per replicate. Those organic originated supplements included phytogenic extracts, organic acid, probiotics or new preparation of anti-bacterial peptides (trade name Halor Tid). The treatment I: pigs were only fed basal diet without antibiotics supplements or other organics feed additives (Negative control). Treatment II: pigs were fed with two antibiotics including colistin 1% and BMD 10% in order to prevent E. coli and Clostridium perfringens infection (Positive control). Pigs in treatment III were fed with a combination of phytogenic extracts, organic acid and probiotics whereas pigs in treatment IV were fed with a combination of phytogenic extracts, organic acid and anti-bacterial peptides. The results showed that the performance parameters such as body weight gain, feed conversion ratio (FCR) and issues of diarrhea and mortality were the worst in the treatment I; whereas these performance parameters in the treatment III or in treatment IV were better than those in treatment II although this difference was not statistically significant at P > 0.05. Besides, the feed cost per kg of live weight of pigs in treatment III and treatment IV was significantly lower than that in treatment I and II.
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References
Duong, K. N., Do, D. T., Dang, A. T. N., Tran, A. T., Tran, K. T. M., Jarchow, A., & Wickern, A. Z. (2019). Investigation of bioactive peptides supplementation in diet for growth performance of weaning-finishing pigs in Vietnam. Journal of Animal Husbandry Sciences and Technics (JAHST) 24, 29-33.
Pearlin, B. V., Muthuvel, S., Govidasamy, P., Villavan, M., Alagawany, M., Farag, M. R., Dhama, K., & Gopi, M. (2020). Role of acidifiers in livestock nutrition and health: A review. Journal of Animal Physiology and Animal Nutrition 104(2), 558-569. https://doi.org/10.1111/jpn.13282.
Rahman, M. R. T., Fliss, I., & Biron, E. (2022). Insights in the development and uses of alternatives to antibiotic growth promoters in poultry and swine production. Antibiotics 11(6), 766. https://doi.org/10.3390/antibiotics11060766.
Silveira, R. F., Roque-Borda, C. A., & Vicente, E. F. (2021). Antimicrobial peptides as a feed additive alternative to animal production, food safety and public health implications: An overview. Animal Nutrition 7(3), 896-904. https://doi.org/10.1016/j.aninu.2021.01.004.
Wang, J. J., Dou, J. X., Song, J., Lyu, F. Y., Zhu, X., Xu, L., Li, Z. W., & Shan, S. A. (2019). Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era. Medicine Research Reviews 39(3), 831–859. https://doi.org/10.1002/med.21542.
Xiao, H., Shao, Y. F., Wu, M. M., Ren, K. W., Xiong, X., Tan, B., & Yin, L. J. (2015). The application of antimicrobial peptides as growth and health promoters for swine. Journal of Animal Science and Biotechnology 6, 19. https://doi.org/10.1186/s40104-015-0018-z.
Xu, B. C., Fu, J., Zhu, L. Y., Li, Z., Wang, Y. Z., & Jin, M. L. (2020). Overall assessment of antimicrobial peptides in piglets: A set of metaanalyses. Animal 14(2), 2463-2471. https://doi.org/10.1017/s1751731120001640.